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I was also at risk of significantly damaging my muscles and joints.

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As you fight to slow your descent against the force of gravity, your muscle fibers literally tear at the microscopic level, causing markers of cellular damage to accumulate in the blood. This peripheral fatigue causes a paradox — you begin looking forward to the uphill sections.

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This, in turn, is thought to increase the incidence of upper respiratory tract infection. My friend Caroline ran with me for 75 miles, endured the worst of the physiological strain, only to take a tumble in the dark and crack her leg on a rock jutting from the ground, forcing her to retire.

The severity of ultra-endurance exercise might result in long-term adaptations that are more commonly linked to disease. These include structural and functional changes in the heart and blood vessels, electrical changes in the cardiac nerves, and possible damage to the heart tissue. Within 30 minutes my legs had completely seized, and I was quickly reduced to the painful protracted shuffle that would be my norm for the next three to four days.


Research has shown that most participants approach ultra-marathons as a means of personal accomplishment — despite its popularity as a competitive sport. For me, the physical and mental hardship were worth the trouble, and I feel proud and content with what I achieved.

Of course, participation is not without its risks — but the greater the adversity the greater the reward. This article is republished from The Conversation under a Creative Commons license.

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Read the original article. View the discussion thread. Skip to main content. An Analysis Teflon and Human Health: Do the Charges Stick?

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Helping Smokers Quit: A Primer for Parents Endocrine Disrupters: Why Aren't There Electric Airplanes? Nick Tiller. Gut instinct According to my heart rate monitor, reaching the finish line cost me 11, calories. Permanent damage? What does running miles look like?


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